Can memantine prevent memory impairment induced by MDMA in humans - Memantine-MDMA
- Conditions
- none
- Registration Number
- EUCTR2010-024543-33-NL
- Lead Sponsor
- Maastricht University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- All
- Target Recruitment
- Not specified
Recreational MDMA users (used at least 3 times of which at least once during the previous year, and maximally 200 times)
Age between 18 and 40 years
Free from psychotropic medication
Good physical health as determined by medical examination and laboratory analysis
Absence of any major medical, endocrine and neurological condition
Normal weight, body mass index (weight/height2) between 18.5 and 28 kg/m2
Written Informed Consent
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range
History of drug abuse (other than the use of MDMA) or addiction
Pregnancy or lactation
Excessive drinking (> 20 alcoholic consumptions a week)
Hypertension (diastolic> 90; systolic> 140)
Current or history of psychiatric disorder
Liver dysfunctioning
(Serious) side effects to previous MDMA use
History of cardiac dysfunctions (arrhythmia, ischemic heart disease,…)
For women: no use of a reliable contraceptive
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method