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Can memantine prevent memory impairment induced by MDMA in humans.

Conditions
MDMA incuded memory impairment
Registration Number
NL-OMON29601
Lead Sponsor
Maastricht University
Brief Summary

/A

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
Not specified
Target Recruitment
16
Inclusion Criteria

1. Recreational MDMA users;

2. Age between 18 and 40 years;

Exclusion Criteria

1. History of drug abuse (other than the use of MDMA) or addiction;

2. Pregnancy or lactation;

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Memory performance is the primary outcome and is measured immediately after each cannabis/placebo treatment. Memory is measured with a verbal memory test and a prospecitve memory test.
Secondary Outcome Measures
NameTimeMethod
Event related potentials are measured while performing the verbal memory tast. P300 will be the outcome measure of the Event related potentials. Measurable and perceptual differences in speech will be studied between MDMA-influenced and non-intoxicated speech.
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