Effects of Physical Training and Nutrition Education on Adipocytokines in Severely Obese Teenagers

Centre Hospitalier Universitaire de Besancon1 site in 1 country32 target enrollmentMarch 2009

ConditionsHealthy Obesity

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Healthy
Sponsor: Centre Hospitalier Universitaire de Besancon
Enrollment: 32
Locations: 1
Primary Endpoint: Adipocytokines (leptin, adiponectin, ghrelin, PAI-1, resistin), based on subject's arterialized capillary blood samples.
Status: Completed
Last Updated: 15 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Obesity is now becoming significantly prevalent of an environment characterized by easily available calorics foods combined with sedentary lifestyles. Moreover, it has been demonstrated that obesity is associated with metabolic complications such as disturbed adipocytokines, hormones secreted by adipose tissue. Given these observations, the purpose of this study is to assess the effects of a lifestyle intervention focused on various physical activities and nutrition education on adipocytokines hormones, in severely obese teenagers.

Registry

clinicaltrials.gov

Start Date

March 2009

End Date

June 2009

Last Updated

15 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

Centre Hospitalier Universitaire de Besancon

Eligibility Criteria

Inclusion Criteria

•to be aged from 12 to 17
•to have a body mass index \> 97 percentile for age and gender
•Exclusion criteria:
•systemic disease
•endocrine disorder
•syndromic obesity
•subjects receiving medication with a history of recent intercurrent illness

Exclusion Criteria

Not provided

Outcomes

Primary Outcomes

Adipocytokines (leptin, adiponectin, ghrelin, PAI-1, resistin), based on subject's arterialized capillary blood samples.

Time Frame: during a lifestyle intervention of 9 months

Secondary Outcomes

Glycemia and lipids profile, based on subject's arterialized capillary blood samples analysis.(during a lifestyle intervention of 9 months)
Insulin resistance, calculated according to the formula of homeostasis model assessment(during a lifestyle intervention of 9 months)
Body weight, body mass index, waist and hip circumference(during a lifestyle intervention of 9 months)
Body composition, calculated by a multifrequency bioelectric impedance(during a lifestyle intervention of 9 months)
Systolic and diastolic blood pressure, measured in millimeters of mercury at the level of the left brachial artery, using an automatic blood pressure monitor.(during a lifestyle intervention of 9 months)