Endoscopic staging and targeted biopsies for routine evaluation of precancerous gastric lesions
Recruiting
- Conditions
- gastric premalignant lesions, intestinal metaplasiavoorstadia maagkanker, intestinale metaplasie
- Registration Number
- NL-OMON27264
- Lead Sponsor
- Erasmus University Medical Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 234
Inclusion Criteria
1. All patients referred to the endoscopy department for an upper gastrointestinal endoscopy for investigation of symptoms, screening or surveillance, who are found to have chronic atrophic gastritis between November 2018 and May 2020.
2. Patients will be over the age of 18 years old.
Exclusion Criteria
1. Patients with gastric neoplasia not amenable to endoscopic resection
2. Patient who do not have an indication for Sydney biopsy staging on standard WLE
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. The diagnostic accuracy for the endoscopic diagnosis of intestinal metaplasia in Sydney biopsy locations
- Secondary Outcome Measures
Name Time Method 1. Reproducibility of endoscopic staging after expert review<br /><br>2. Reproducibility of histopathology for detection of intestinal metaplasia<br /><br>3. Number of dysplastic or neoplastic lesions detected<br /><br>4. Longer inspection time of gastric mucosa increases accuracy<br>