Comprehensive characterization of alcohol-induced postural instability and walking ataxia in healthy participants: a new model to mimic sensory and cerebellar ataxia?

Not Applicable

• Conditions: ataxic gait; R27.0; Ataxia, unspecified

• Registration Number: DRKS00029699
• Lead Sponsor: Zentrum für Schwindel und GleichgewichtsstörungenUniversitätsspital Zürich

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-07-19
• Study Completion: 2023-07-28
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

Signed informed consent
- absence of exclusion criteria

Exclusion Criteria

- Alcohol dependence or intolerance
- pregnant or breastfeeding women
- every orthopedic, neurological or systemic disease affecting walking or postural balance

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in gait parameters that are characteristic for ataxic disorders (variability in step length and trunk sway) as a function of gait speed under the influence of alcohol.

Secondary Outcome Measures

Name	Time	Method
- Change in the subscores of condition five and six (postural control via vestibular/cerebellar networks) in the sensory organization test (SOT) under the effect of alcohol.<br>- Change in the adaptation to postural perturbations under the effect of alcohol.<br>- Change in the accuracy of arm movements in the finger-to-nose test under the effect of alcohol.