Development of Alcohol Use Disorders: the role of clinical, psychological, environmental and neurobiological factors; an fMRI substudy
Completed
- Conditions
- Alcohol dependencydepression10037176
- Registration Number
- NL-OMON33738
- Lead Sponsor
- Vrije Universiteit Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 80
Inclusion Criteria
Per group: (I) current DSM-IV diagnosis alcohol dependency and 6 month DSM-IV diagnosis of depression and/ or anxiety disorder; (II) 6-month DSM-IV diagnosis depression and/or anxiety disorder; (III) No DSM-IV psychiatric disorder
Exclusion Criteria
(a) the use of psychotropic medication except for selective serotonin reuptake inhibitors in stable dosage, (b) major internal or neurological disorder, (c) known contra-indications for MR investigations, such as the presence of metal objects (e.g. pacemaker, arteriovenous clips), or claustrophobia
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Behavioural data and Blood Oxygenated Level Dependent (BOLD)-response, recorded<br /><br>using fMRI, will be measured. These, and behavioural data are correlated with<br /><br>chronicity of alcohol dependence in order to investigate weather differences in<br /><br>several cognitive and motivational activities underlie the differences in<br /><br>chronicity of alcohol dependence. </p><br>
- Secondary Outcome Measures
Name Time Method <p>nvt</p><br>