Dysfunctional neuronal networks in alcoholism: Utilizing translational neuroimaging to identify altered brain connectivity and treatment efficacy predictors
Recruiting
- Conditions
- F10.2
- Registration Number
- DRKS00003357
- Lead Sponsor
- Zentralinstitut für Seelische Gesundheit
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 270
Inclusion Criteria
alcohol dependence (DSM IV; ICD 10) and
average84g of pure alcohol per day during the last 90 days
Exclusion Criteria
other Axis 1 psychiatric diagnoses than alcohol- or nicotine-dependence in the last 12 months, common exclusion criteria for MRI, positive urine drug screen, severe medical illness and history of brain injury
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To determine differences in functional connectivity between alcohol addicted patients and healthy controls using rsfMRI and DTI<br><br>
- Secondary Outcome Measures
Name Time Method To determine differences in functional connectivity between alcohol addicted patients treated with Naltrexone or Acamprosate vs. alcohol addicted patients without medication using rsfMRI and DTI