Effect of a Polypill on middle-aged and elderly Iranians
Completed
- Conditions
- Cardiovascular disease in middle-aged and older adults.Circulatory SystemCardiovascular disease
- Registration Number
- ISRCTN43076122
- Lead Sponsor
- Ministry of Health and Medical Education (Iran)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 500
Inclusion Criteria
1. Men between the ages of 50 and 80 (inclusive)
2. Women aged 55 to 80 (inclusive)
3. Living in Kalaleh
4. Free from existing cardiovascular disease (stroke, Transient Ischaemic Attack [TIA], Myocardial Infarction [MI], or angina)
5. Not currently be taking or eligible for antihypertensive treatment, aspirin or statins
Exclusion Criteria
1. Total cholesterol levels exceed 240 mg/dL
2. Blood pressure exceeds 160/100 mmHg at baseline
3. People with existing vascular disease
4. Clear indication or contra-indication for any component of the polypill or other chronic medical problems that would interfere with participation
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Combined cardiovascular events (MI, new onset angina, coronary artery surgery, stroke or sudden cardiac death)
- Secondary Outcome Measures
Name Time Method 1. Total mortality <br>2. Gastrointestinal bleeding