Standard versus High Protein Enteral Feeding

Not Applicable

• Conditions: Nutritional, Metabolic, Endocrine

• Registration Number: PACTR202006791593580
• Lead Sponsor: Faculty of Medicine Tanta University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-02-22
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

?Adult Brain Trauma patients of both sexes
Glasgow Coma Scale = 8 and an injury severity score (ISS>15)
who were admitted to our ICU within 24 hours after the injury.
only well-nourished ( Modified Nutric –Score for Risk Screening = 0- 4) (10), previously healthy subjects will be recruited

Exclusion Criteria

?Pregnancy,
?Vascular insufficiency or trauma to the lower limbs,
?History of neuromuscular diseases,
?Prolonged immobility prior to ICU admission,
? Comorbidities (renal, hepatic, cardiac disorders, chronic obstructive pulmonary disease, and diabetic patient),
?Patients with BMI = 35 ,
?Patients with malignant diseases or immune disorders,
? Prolonged corticosteroids (CS) and/ or neuromuscular blocking agents (NMBA) use ,
?ARDS patient (P/F ratio = 200),
?Sepsis, Multiorgan failure.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
the percentage of reduction in the muscle mass measured by US.

Secondary Outcome Measures

Name	Time	Method
-Pennation angle, cross sectional area, and Echogenicity of rectus femoris muscle, ;Length of mechanical ventilation and ICU stay