A study of the efficacy and safety of microneedle patch containing triamcinolone acetonide and hydrocortisone in the treatment of inflammatory acne

Phase 1

Recruiting

• Conditions: inflammatory acne

• Registration Number: TCTR20220830003
• Lead Sponsor: ational Research Council of Thailand

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-08-30
• Last Update Posted: 19 August 2024
• Study Completion: 2025-01-31

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

1. Both male and female with age of 18 to 60 years old
3. Have inflammatory papular/pustular acne with 5 mm in size or more, for at least 4 lesions on the face

Exclusion Criteria

1. receive topical corticosteroid or intralesional corticosteroid within 2 weeks before recruitment
2. receive ablative or non-ablative laser therapy on the face within 2 weeks before recruitment
3. receive oral corticosteroid within 8 weeks before recruitment
4. have active contact dermatitis, rash, eczema or skin infection on the face where the treatment will be located
5. History of triamcinolone, hydrocortisone, hyaluronic acid allergy or have severe intralesional corticosteroid injection adverse effects
6. are in pregnancy or breastfeeding period
7. are unable to promptly visit the office for follow-up session

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Acne size 2, 3, 4, 7, 14 and 28 day Vernier caliper

Secondary Outcome Measures

Name	Time	Method
Erythema index 2, 3, 4, 7, 14 and 28 days Antera 3D,Melanin index 2, 3, 4, 7, 14 and 28 days Antera 3D,Erythema index 2, 3, 4, 7, 14 and 28 days colorimeter,Melanin index 2, 3, 4, 7, 14 and 28 days colorimeter