Microneedling with tranexamic acid and also microneedling with vitamin C for the treatment of melasma
Phase 2
Recruiting
- Conditions
- Melasma.ChloasmaL81.1
- Registration Number
- IRCT20210608051516N1
- Lead Sponsor
- Ahvaz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 34
Inclusion Criteria
Women 18 to 50 years old with symmetrical and bilateral facial melasma
Exclusion Criteria
Pregnant women and breastfeeding mothers
Taking oral contraceptive pills during the last 12 months and during the study
Existence of any history of coagulation disorders and thrombotic problems
Taking Medicines anticoagulants and anticonvulsants
Existence of allergy to studied drugs and topical lidocaine
History of melasma treatment in the past month
Active facial herpes simplex lesions
Facial warts
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Melasma area and severeity index score (MASI SCORE). Timepoint: It is done at the beginning of the study and weeks 2, 4, 8 and 12. Method of measurement: Face photography with camera.;Recovery rate of melasma lesions. Timepoint: It is done at the beginning of the study and weeks 2, 4, 8 and 12. Method of measurement: Face photography with camera.
- Secondary Outcome Measures
Name Time Method Patient satisfaction with melasma treatment. Timepoint: ????????????4 weeks after treatment. Method of measurement: questionnaire.