Effect of Vitamin D supplementation on osteodystrophy in patients with chronic liver disease

Not Applicable

Completed

• Conditions: Health Condition 1: null- Chronic liver disease

• Registration Number: CTRI/2015/04/005674
• Lead Sponsor: Indian Council of Medical Research

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

All the consecutive patients with CLD (irrespective of the etiology and the disease severity) having vitamin D deficiency along with hepatic osteodystrophy would be enrolled

Exclusion Criteria

1.Patients undergoing recent contrast study or nuclear medicine test.

2.Pregnant or lactating women

3.Patients with related thyroid, parathyroid disease, cushingâ??s syndrome, diabetes, malignancies, cardiovascular, pulmonary, and renal disease.

4.Patients with a history of immobilization in the past, known cases of osteoporosis on anti-osteoporotic drugs

5.Women with surgical menopause

6.Patients receiving calcium and vitamin D supplementation for <4 weeks before enrollment

7.Patients receiving medications like steroids, HRT, calcitonin, bisphosphonates, anti-coagulants, anticonvulsants, thyroxine, antiepileptics, interferon, immunosuppressive agents, cholestryamine.

8.Patients with hemachromatosis and Wilsonâ??s disease

9.Patients who refuse to participate in the study

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in level of vitamin D and Bone Mineral Density <br/ ><br> <br/ ><br> <br/ ><br>Timepoint: Baseline and 1 Year <br/ ><br> <br/ ><br>

Secondary Outcome Measures

Name	Time	Method
ILTimepoint: NI