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临床试验/NCT05794867
NCT05794867已完成不适用

Comparative Study Between Use of Ultrasonic Criteria of Weaning Versus the Conventional Criteria of Weaning in Post-traumatic Acute Respiratory Distress Syndrome Patients Who Were Ventilated for a Long Time

King Abdul Aziz Specialist Hospital1 个研究点 分布在 1 个国家目标入组 200 人开始时间: 2021年4月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
200
试验地点
1
主要终点
The number of patients who had no failure of weaning

研究概览

简要总结

compare and evaluate the effect of use of ultrasonic criteria of weaning versus the conventional ways of weaning in post-traumatic acute respiratory distress syndrome (ARDS) patients who were ventilated for a long time. And compare their effect on the duration of ICU stay.

详细描述

It is a prospective double blind study done on total 200 patients. Who were weaned from ventilator after being ventilated for > one week due to respiratory failure. This respiratory failure was selected in our study to be from severe lung contusion and post-traumatic acute respiratory distress syndrome. Patients were randomly allocated in one of two groups each group contain 100 patients. Group A considered control group. Those patients weaned from the ventilator by the conventional criteria of weaning. While group B weaned from the ventilator by the ultrasound criteria of weaning. All patients weaned from both groups followed for six days for signs of failure of weaning ,signs of post-extubation respiratory failure. And number of patients who were re-ventilated and who discharged from ICU in both groups recorded and compared.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • adult patients between 18-65 years old,
  • with Acute respiratory distress syndrome,
  • any ventilated patients for more than one week

排除标准

  • young or pediatric patients below 18 years.
  • patients older than 65 years
  • patients had Chronic Respiratory Disease

结局指标

主要结局

The number of patients who had no failure of weaning

时间窗: 6 days

patients followed by ultrasounds criteria

次要结局

  • The number of patients who discharged early from ICU(6 days)

研究者

发起方
King Abdul Aziz Specialist Hospital
申办方类型
Network
责任方
Sponsor

研究点 (1)

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