Comparison between an injection treatment of botulinum toxin A and an oral tablet glycopyrrolate in patients of cerebral dysfunction with complaints ofexcessive salivatio
- Conditions
- Health Condition 1: G80- Cerebral palsy
- Registration Number
- CTRI/2023/07/055549
- Lead Sponsor
- Institute of Postgraduate Medical Education and Research
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
1.Confirmed case of cerebral palsy.
2.Drooling Severity (DS) Scale score 3 or more.
3.Drooling Frequency (DF) scale score 3 or more.
4.Consent from the guardian or relative
1.Local site infection. 2.Allergy to botulinum toxin type A or oral Glycopyrrolate.
3.H/O severe Dysphagia.
4.H/O surgery done for controlling of sialorrhea. Or any h/o of salivary gland excision surgery mainly parotid and submandibular. 5.Abnormal coagulation profile. 6.Patients suffering from unstable cardio vascular or serious respiratory diseases.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ltrasound guided botulinum toxin type A injection to salivary glands (b/l parotid & submandibular) versus otal glycopyrrolate in sialorrhea in cerebral palsy patients will be compared for efficacyTimepoint: 1 year
- Secondary Outcome Measures
Name Time Method Improvement of quality of life physically & psychologically following application of botulinum toxin type A injection over oral glycopyrrolate therapy will be compared.Timepoint: 1 year
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