Determinants of Functional Capacity in Children With Asthma

Completed

• Conditions: Asthma in Children
• Interventions: Other: 6-minute walk test; Other: Pulmonary function test; Other: Respiratory muscle strength test; Other: Lower extremity muscle strength test

• Registration Number: NCT05963919
• Lead Sponsor: Atlas University

Brief Summary

The primary aim of this study is to compare the respiratory function, respiratory muscle strength, functional capacity, and lower extremity strength of children with asthma and healthy children in the same age group. The secondary aim of our study is to determine the determinants of functional capacity in children with asthma.

Detailed Description

Not available

Study Timeline

• Study Start: 2023-01-01
• Primary Completion: 2023-06-30
• Study Completion: 2023-06-30
• Status Verified: 2023-07
• Study First Submitted: 2023-07-18
• Study First Submitted QC: 2023-07-18
• Last Update Submitted: 2023-07-18
• Study First Posted: 2023-07-27
• Last Update Posted: 2023-07-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Being between the ages of 6-17
• Being diagnosed with asthma
• Able to walk, cooperate and clinically stable
• Being a volunteer to participate in the study
• To be able to speak, read, understand, and cooperate in Turkish

Asthma Group

Exclusion Criteria

• History of previous lung or liver transplant
• Having an acute exacerbation and/or a history of hospitalization in the last 1 month
• Having diagnosed orthopedic problems affecting mobility or a history of musculoskeletal surgery

Control Group Inclusion Criteria:

• Being between the ages of 6-17
• To be able to speak, read, understand, and cooperate in Turkish
• Being a volunteer to participate in the study

Control Group Exclusion Criteria:

• Having a diagnosed vision, hearing, or neurological disease that may affect balance
• Having any other neurological, orthopedic, cardiovascular, thoracic, or metabolic disease or pathological condition that would affect assessments
• Resting saturation below 90% during exercise tests

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Asthma Group	6-minute walk test	6 minute walk test, Pulmonary function test, Respiratory muscle strength test, Lower extremity muscle strength test
Asthma Group	Respiratory muscle strength test	6 minute walk test, Pulmonary function test, Respiratory muscle strength test, Lower extremity muscle strength test
Control Group	6-minute walk test	6 minute walk test, Pulmonary function test, Respiratory muscle strength test, Lower extremity muscle strength test
Control Group	Pulmonary function test	6 minute walk test, Pulmonary function test, Respiratory muscle strength test, Lower extremity muscle strength test
Control Group	Respiratory muscle strength test	6 minute walk test, Pulmonary function test, Respiratory muscle strength test, Lower extremity muscle strength test
Control Group	Lower extremity muscle strength test	6 minute walk test, Pulmonary function test, Respiratory muscle strength test, Lower extremity muscle strength test
Asthma Group	Pulmonary function test	6 minute walk test, Pulmonary function test, Respiratory muscle strength test, Lower extremity muscle strength test
Asthma Group	Lower extremity muscle strength test	6 minute walk test, Pulmonary function test, Respiratory muscle strength test, Lower extremity muscle strength test

Primary Outcome Measures

Name	Time	Method
Forced expiratory volume in 1 second (FEV1)	10-15 minutes
6-minute walk test	15-20 minutes
Peak expiratory flow (PEF)	10-15 minutes
Maximal inspiratory pressure (MIP)	15-20 minutes
Maximal expiratory pressure (MEP)	15-20 minutes
Lower extremity muscle strength	5-10 minutes

Trial Locations

Locations (1)

Istanbul Atlas University; 🇹🇷 Istanbul, Turkey