Study of the Characteristics of Pruritus in Patients With Frontal Fibrosing Alopecia or Lichen Planus Pilaris

Terminated

• Conditions: Alopecia; Lichen Planus
• Interventions: Other: questionnaire

• Registration Number: NCT05761158
• Lead Sponsor: University Hospital, Brest

Brief Summary

The prevalence of pruritus has been studied in frontal fibrosis alopecia (FFA) and lichen planus pilaris (LPP), but there are no studies evaluating the characteristics of pruritus, the correlation between pruritus and disease activity, and its impact on quality of life.

The knowledge of the characteristics of pruritus, of the link "disease activity - pruritus", and its impact on the quality of life could allow us to modify the management of the patient (modification or intensification of therapy, close monitoring...)

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2023-02-01
• Study First Submitted QC: 2023-02-27
• Study First Posted: 2023-03-09
• Study Start: 2023-03-14
• Primary Completion: 2023-05-25
• Study Completion: 2023-05-25
• Status Verified: 2025-01
• Last Update Submitted: 2025-04-22
• Last Update Posted: 2025-04-24

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 21

Inclusion Criteria

• Major patient.
• Fibrosing frontal alopecia or lichen planus pilaris
• Presence of pruritus of the scalp : a positive response to the question "do you experience itchy scalp?"
• The patient received an information note and did not object to the study

Exclusion Criteria

• Patients under 18 years of age.
• Other pathologies causing scalp pruritus (seborrheic dermatitis, contact dermatitis, lupus, Quinquaud's decalcifying folliculitis, ectoparasitosis, scalp psoriasis, ringworm, red sclap syndrome, dermatomyositis, central centrifugal cicatricial alopecia (CCCA))
• Refusal to participate by the patient.
• Patient under legal protection (curatorship, guardianship, ...)
• Patient not covered by social security

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
patient	questionnaire	patients answer the same questionnaire whether they have frontal alopecia or lichen planus pilaris

Primary Outcome Measures

Name	Time	Method
Study of the characteristics of pruritus in patients with frontal fibrosis alopecia or lichen planus pilaris	Hour1	Questionnaire of Brest
Study of the characteristics of pruritus in patients with frontal fibrosis alopecia or lichen	Hour1	5D itch scale

Secondary Outcome Measures

Name	Time	Method
Study the relationship between disease activity (AFF or LPP) and pruritus, as well as the impact of pruritus on patients' quality of life.	Hour1	Questionnaire of LPPAI

Trial Locations

Locations (1)

CHU Brest; 🇫🇷 Brest, France