A study comparing recovery features of patients undergoing general anaesthesia with rocuronium as muscle relaxant and recieving sugammadex or neostigmine and glycopyrollate for reversal.
- Conditions
- Health Condition 1: K402- Bilateral inguinal hernia, withoutobstruction or gangreneHealth Condition 2: K800- Calculus of gallbladder with acutecholecystitisHealth Condition 3: N920- Excessive and frequent menstruation with regular cycle
- Registration Number
- CTRI/2024/04/065600
- Lead Sponsor
- Manipal Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
American Society of Anesthesiologists grades 1, 2, and 3 patients aged 18–60 years, coming for elective laparoscopic surgeries (lasting one to three hours) will be recruited for the study.
1. Patients with cardiorespiratory abnormalities (New York Heart Association heart failure grades 3 and 4.
2. Known allergy to Rocuronium.
3. Renal insufficiency (eGFR <60).
4. Liver dysfunction (liver enzymes—serum glutamic oxaloacetic transaminase/ serum glutamic pyruvic transaminase values elevated by more than 50% of normal).
•Underlying neuromuscular disease or the use of drugs known to interfere with neuromuscular transmission.
•Intraoperative hypothermia (core temperature less than 35°C).
•Known Emphysema.
•Unwillingless to perform PFT.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Time taken for complete reversal of neuromuscular blockTimepoint: Reversal given at TOF count of 2 and time taken to reach TOF ratio 0.9. It is checked at the end of each case at the time of extubation.
- Secondary Outcome Measures
Name Time Method To compare post operative respiratory function in terms of PFTTimepoint: PFT to be done in post anaesthesia care unit 20 minute after extubation