A comparison of low flow anesthesia with gas monitor vs high flow anesthesia during laparoscopic cholecystectomy A Randomized controlled study
试验速览
- 阶段
- Phase 3 4
- 状态
- 尚未招募
- 发起方
- 入组人数
- 70
- 试验地点
- 1
- 主要终点
- To measure the amount of inhalation agent sevoflurane during laparoscopic surgery with or without gas monitor.
研究概览
简要总结
Low flow anesthesia is defined to be an inhalation anesthetic technique via a rebreathing system in which the rebreathing fraction at least amounts to 50 % (i.e. 50% of the exhaled gas volume is led back to the patient after carbon dioxide absorption in the next inspiration[3].During low flow anesthesia , for the safe conduct of anesthesia , continuous monitoring of the anesthetic agent concentration should consider mandatory. The main advantages of low flow techniques are economy, climatization of the inspired gases, and reduced atmospheric pollution[3].Low flow anesthesia with one of the third generation halogenated anesthetic, desflurane or sevoflurane has shown cost
effective and is becoming more and more commonly adopted.
Gas monitor shows anesthetic gas concentration and MAC values of inhalation gases which enhances patient’s safety during anesthesia periods.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 20.00 Year(s) 至 50.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients willing to sign inform consent.
- •Patients undergoing elective laparoscopic cholecystectomy surgeries under general anesthesia aged between 20 and 50 years.
- •Patients belonging to American Society of Anaesthesiologist physical status !and II.
排除标准
- •Patients refused.
- •All below 20 and above 50 years.
- •Patients with ASA III or more.
- •Patients with known allergy, sensitivity or any other form of reactionn to any drug.
- •Patients with systemic comorbidities.
结局指标
主要结局
To measure the amount of inhalation agent sevoflurane during laparoscopic surgery with or without gas monitor.
时间窗: 0,3,5,10,15,30,45,60,75,90,105,120 minutes
To observe the hemodynamic parameter,oxygen saturation and end tidal CO2,N2O
时间窗: 0,3,5,10,15,30,45,60,75,90,105,120 minutes
次要结局
- To observe side effect or complication durinng peri operative periods.(0,3,5,10,15,30,45,60,75,90,105,120 minutes)
研究者
Dr Jatin B Patel
Sumandeep vidyapeeth deemed to be University