The Connection between Mechanical Alternans measured by Pressure-Volume (PV) Loop catheter in Patients with Ischemic Heart Failure and the Occurrence of Microvolt T wave Alternans (MTWA).

• Conditions: heart failure; reduced heart function; 10019280

• Registration Number: NL-OMON34243
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 10

Inclusion Criteria

Patients will be included if they are over 18 years and under 85 years and able to give informed consent. Patients with heart failure caused by coronary artery disease. LVEF * 35% measured by echocardiogram. Patients with an indication for electrophysiological examination.

Exclusion Criteria

hemodynamically instable patients
age under 18 and over 85 years
heart failure not caused by coronary artery disease
severe co-morbidity

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Presence or absence of mechanical alternans and MTWA.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Differences in reduced or more preserved LVEF and the occurrence of the two<br /><br>phenomena<br /><br>Occurrence of ventricular tachyarrhythmic events<br /><br>Influence of LV compliance on arrhythmogenesis of the infarction border zone.</p><br>