Efficacy of additional Calcineurin inhibitors in anti TNF-alfa antibody refractory Ulcerative colitis
Not Applicable
Recruiting
- Conditions
- lcerative colitis
- Registration Number
- JPRN-UMIN000024936
- Lead Sponsor
- Keio University Gastroenterology and Hepatology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Not provided
Exclusion Criteria
1 Patients with severe Ulcerative colitis. 2 Patients with colitis except for Ulcerative colitis. 3 Patients with gastrointestinal obstruction. 4 Preoperation patients. 5 Patients with severe infection. 6 Patients with severe heart disease. 7 Patients with serum creatinine above 1.2. 8 Patients with serum total Bilirubin above 2.0, AST above 50, ALT above 50. 9 Patients with malignancy or history of malignancy. 10 Patients with neuropsychiatric disorder. 11 women who are or may be pregnant, nursing women and woman who desire to bear children. 12 Inappropriate patients by doctor's judgement. 13 Patients who received a part of other UC therapies.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method primary outcome is efficacy at 6 months. Effective is partial Mayo score <3.
- Secondary Outcome Measures
Name Time Method