Polyphenol Rich Supplementation on Markers of Recovery From Intense Resistance Exercise

Phase 1

• Conditions: Muscle Soreness
• Interventions: Dietary Supplement: Tart Cherry; Other: Placebo Oral Capsule [CEBOCAP]

• Registration Number: NCT03540602
• Lead Sponsor: Jacksonville University

Brief Summary

Strength training is commonly used as an intervention to increase muscle mass, thus improving a person's ability to undertake activities of daily living, or enhance athletic performance. The strength training regimen itself, while ultimately having beneficial effects, causes muscle fibers to be damaged, which the body has to recover from. As the body recovers, it rebuilds the muscle tissue and after multiple consecutive bouts of strength training, the muscle eventually becomes larger and stronger. Thus, it is the recovery from strength training exercise that ultimately determines how well the body adapts. Where inadequate recovery could eventually lead to overtraining and/or injury, optimizing the recovery process from strength training could maximize strength training adaptations. This concept of optimizing recovery has led to development of many supplements, including antioxidants, which may reduce the damage associated with strength training activities and therefore enhance positive adaptations. The purpose of this study is to assess the ability of a polyphenol rich supplementation to aid the recovery process from a demanding bout of resistance exercise

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2018-02-26
• Status Verified: 2018-05
• Study Start: 2018-05-01
• Study First Submitted QC: 2018-05-16
• Last Update Submitted: 2018-05-16
• Study First Posted: 2018-05-30
• Last Update Posted: 2018-05-30
• Primary Completion: 2018-08
• Study Completion: 2018-08

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Male
• Target Recruitment: 20

Inclusion Criteria

• 6 months of resistance training experience with barbel back squat exercise

Exclusion Criteria

• Not currently taking any antioxidant supplements, not currently using any hormone replacement therapy or anabolic androgenic steroids.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Polyphenol Rich Supplement	Tart Cherry	NordicCherry Tart Cherry Extract Powder 500 mg in capsule form
Placebo	Placebo Oral Capsule [CEBOCAP]	Rice flour capsule

Primary Outcome Measures

Name	Time	Method
Assessment of Oxidative Stress	7 weeks	Blood analyses will be used, 8 mL of blood will be taken from the participant six times per condition. The blood will be centrifuged to separate the serum/ plasma and analyzed by enzyme- linked immunosorbent assay (ELISA) for c- reactive protein and creatine kinase, and oxidative damage

Secondary Outcome Measures

Name	Time	Method
Muscle soreness	7 weeks	Subjects will mark a line on a 10cm scale that corresponds to the amount of muscular soreness they currently perceive
Vertical Jump Performance	7 weeks	Subjects will be instructed to stand on a NeuroCom Balance Manager forceplate with hands on hips. Subjects will then be instructed to perform 3 consecutive vertical jumps, as high as possible with minimal time between jumps. The jumps will later be assessed for power production.

Trial Locations

Locations (1)

Jacksonville University; 🇺🇸 Jacksonville, Florida, United States