Assessment of disease activity with quantitative joint power Doppler ultrasonography in patient with rheumatoid arthritis - Assessment of disease activity with quantitative joint power Doppler ultrasonography in patient with rheumatoid arthritis

Center for Rheumatic Diseases, Tokeidai Memorial Hospital0 sites20 target enrollmentJune 18, 2009

Overview

Phase: 未知
Intervention: Not specified
Conditions: Not specified
Sponsor: Center for Rheumatic Diseases, Tokeidai Memorial Hospital
Enrollment: 20
Status: Completed
Last Updated: 2 years ago

Overview Investigators Eligibility Criteria Outcomes Similar Trials

Overview

Brief Summary

Results: Quantitative power Doppler ultrasonography (PDUS) was significantly correlated with enhancement rate of MRI in each single finger joint. Comparing quantitative synovial vascularity and radiographic change in single MCP or PIP joint, the level of vascularity at baseline showed significant positive correlation with radiographic progression at the 20th week. The change of vascularity responded to DMARDs, defined as the percentage change in vascularity by the 8th week from baseline, was inversely correlated with radiographic progression in each MCP joint. Quantitative PDUS method was more useful than semi-quantitative method for the evaluation of synovial vascularity in single finger joint.

Registry

who.int

Start Date

June 18, 2009

End Date

January 1, 2010

Last Updated

2 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

Center for Rheumatic Diseases, Tokeidai Memorial Hospital

Eligibility Criteria

Inclusion Criteria

Not provided

Exclusion Criteria

•Patients who fulfill one of the following criteria must be excluded: 1\) Patients who have apparent infection 2\) Female patients who are during pregnancy or lactation 3\) Patients who are judged to be inappropriate by investigator