Comparison of analgesic efficacy of dexmedetomidine as an adjuvant to 0.25% Bupivacaine vs. Plain 0.25% bupivacaine in ultrasound-guided pudendal nerve block in children undergoing perineal procedures: A prospective, randomized comparative study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 44
- 试验地点
- 1
- 主要终点
- Determine the effects of the intervention as duration of analgesia as first time to rescue analgesic
研究概览
简要总结
Perioperative pain management in pediatric patients is essential for enhancing recovery and minimizing postoperative complications. Pudendal nerve block, a
regional anesthesia technique, is increasingly preferred for perineal surgeries as it provides targeted analgesia, reduces systemic opioid use, and minimizes complications associated with central neuraxial blocks, such as dural puncture, motor block, and urinary retention. Among local anesthetics, bupivacaine is widely used for its efficacy and prolonged action. However, the addition of adjuvants like
dexmedetomidine has shown promise in enhancing analgesia. in this study, we are comparing the efficacy of dexmeditomidine as an adjuvant to 0.25% bupivacaine.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 6.00 Month(s) 至 7.00 Year(s)（—）
- 性别
- All
入选标准
- •Age 6 months to 7 years ASA physical status I- II Scheduled to undergo elective perineal surgeries- circumcision, hypospadias, PUJ fulguration, chordee repair.
排除标准
- •Parent refusal History of allergic reactions to local aesthetics Bleeding diathesis Rash or infection at the injection site Anatomical spinal abnormality Liver diseases.
结局指标
主要结局
Determine the effects of the intervention as duration of analgesia as first time to rescue analgesic
时间窗: timeline assessed at baseline, every 5minutes till 90 minutes intraoperatively and till 24 hours post operatively.
次要结局
- success of block(Quality of recovery score)