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临床试验/CTRI/2019/09/021393
CTRI/2019/09/021393招募中未知

Range of salivary cortisol (morning and late-night), and Overnight dexamethasone suppressed serum and salivary cortisol in chronic renal failure patients.

Department of endocrinology KEM hospital0 个研究点目标入组 0 人开始时间: 待定最近更新:

试验速览

阶段
未知
状态
招募中
发起方

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

入选标准

  • 1. Patients with clinically stable CKD will be divided on the basis of glomerular filtration rate (GFR) into the following arbitrary four groups: mild (GFR: 60-89 ml/min/1.73 m2), moderate (GFR: 30-59 ml/min/1.73 m2) and severe kidney insufficiency (GFR: 15-29 ml/min/1.73 m2), and patients on haemodialysis. 30 patients from each group, and in addition 30 healthy controls with normal GFR >90 ml/min/1.73 m2) will be recruited.

排除标准

  • 1. Patients on exogenous steroid therapy.
  • 2. Subjects on drugs known to alter
  • Dexamethasone metabolism or CBG (cortisol
  • Binding Globulin) status.
  • 3. Patients having gingivitis or oral ulcers.
  • 4. Oral tobacco use
  • Exclusion Criteria for Healthy Volunteers:
  • 1. Pregnancy
  • 2. Subjects on drugs known to alter
  • Dexamethasone metabolism or CBG (cortisol
  • Binding Globulin) status.
  • 3. Subjects having gingivitis or oral ulcers.
  • 4. Oral tobacco use

研究者

发起方
Department of endocrinology KEM hospital

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