Effect of combination of Propofol-Remifentanil vs Ketofel in duration of seizure and hemodynamic signs of psychotics patient in electroconvulsive therapy

Phase 2

Recruiting

• Conditions: psychotics patient.; Psychotic disorder with hallucinations due to known physiological condition; F06.0

• Registration Number: IRCT20141209020258N129
• Lead Sponsor: Arak University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 February 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 105

Inclusion Criteria

18 to 50 years
Patients with a diagnosis of major schizophrenia depression of catatonia or bipolar disorder
ASA class I and II

Exclusion Criteria

Sensitivity to medications used
Drug history
History of cardiovascular disease
Pregnancy
Patients in need of treatment for hemodynamic instability following seizures, who had less than 25 second tonic or clonic seizures, or had more than 60% energy to induce seizures

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Mean arterial pressure. Timepoint: At baseline, 1, 2, and 3 minutes after shock and after recovery. Method of measurement: Barometer.;Heart rate. Timepoint: At baseline, 1, 2, and 3 minutes after shock and after recovery. Method of measurement: Count.;Oxygen saturation percentage. Timepoint: At baseline, 1, 2, and 3 minutes after shock and after recovery. Method of measurement: Pulse oximetry.;Duration of seizures. Timepoint: After electro convulsive therapy. Method of measurement: Minute.