Effect of Fish oil supplementation on inflammation of blood vessels in people with heart disease

Not Applicable

Completed

• Conditions: cardiovascular disease (CVD); arterial inflammation; Cardiovascular - Coronary heart disease; Inflammatory and Immune System - Other inflammatory or immune system disorders

• Registration Number: ACTRN12621000377831
• Lead Sponsor: The University of Western Australia

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-04-01
• Study Completion: 2023-01-12
• Last Update Posted: 27 March 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 12

Inclusion Criteria

aged between 45-69 years of age with elevated fasting Lp(a) levels (>0.5g/L), stable coronary artery disease and on maximally tolerated doses of lipid-lowering therapy, including a statin, and achieving a fasting LDL-cholesterol of <4.0 mmol/L. Stable coronary artery disease will be defined as previous coronary event (myocardial infarction, stroke, re-vascularisation procedure) >3 months ago or established coronary artery calification (>400) following CT coronary angiogram.

Exclusion Criteria

unstable coronary artery disease or a cardiovascular event within the last 3 months, fasting blood sugar level >7.2 mmol/L, tachyarrhthmias, women who are pregnant or lactating, a previous diagnosis of a severe co-existing medical condition that would prevent participation (eg: severe dementia or terminal illness), <45 or >70 years of age, or unable to provide a written informed consent.

Study & Design

• Study Type: Interventional
• Study Design: Not specified