Association Of Prognosis And BRAF V600E Mutations In Papillary Thyroid Carcinoma
试验速览
- 阶段
- 早期 1 期
- 入组人数
- 150
- 试验地点
- 2
- 主要终点
- BRAF V600E MUTATION
研究概览
简要总结
The purpose of this study is to determine whether BRAF V600E mutation in our patients with papillary thyroid cancer has an association with poor prognosis.
详细描述
Papillary thyroid carcinoma (PTC) is the most common type of thyroid malignancy and BRAF V600E mutation is the most common genetic alteration identified in PTC, ranging from 25 to 80%, with the average rate about 45%. Various studies demonstrated a relationship between BRAF V600E mutation and aggressive characteristics of the cancer, including the worse patient prognosis. But,there are no studies from Turkey regarding this topic. So the investigators will examine BRAF V600E mutation in our patients with PTC and try to assess the role of this mutation in prognosis and further management of the patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with papillary thyroid cancer
排除标准
- •Patients who do not want to be a part of this study
结局指标
主要结局
BRAF V600E MUTATION
时间窗: 2 years
次要结局
未报告次要终点