change in the level of blood immunity before and after epidural anesthesia in patients undergoing breast cancer surgery
Not Applicable
- Conditions
- Health Condition 1: C509- Malignant neoplasm of breast of unspecified site
- Registration Number
- CTRI/2022/01/039127
- Lead Sponsor
- Amrita Institute of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
ASA 2 patients who are scheduled for breast surgeries for breast cancer under epidural anaesthesia
Exclusion Criteria
1.Any contraindication for regional anaesthesia
2.Patients who have difficulty in lying down supine
3.Uncooperative/ Psychiatric patients
4.Endocrinological diseases
5.Immunological diseases
6.Chronic liver disease
7.Chronic pain
8.Signs of infection
9.Allergic to any of the study medication
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To assess the change in proinflammatory mediator IL6 before and after epidural anaesthesiaTimepoint: Before and 2 hours after anaesthesia
- Secondary Outcome Measures
Name Time Method To assess the change in serum levels of TNF α, IL1β, IL10, IFN γ, IL 2, leucocytes, lymphocytes, neutrophils, monocytes, eosinophils and basophils caused by induction of epidural anaesthesia.Timepoint: Before and 2 hours after anaesthesia