Respiratory and Submental Muscles Activity During Inspiration and Expiration in Obstructive Sleep Apnea Syndrome

Completed

• Conditions: Obstructive Sleep Apnea

• Registration Number: NCT04103073
• Lead Sponsor: Hacettepe University

Brief Summary

In this study respiratory and submental muscle activities during during inspiratory and expiratory breathing maneuver at specific workloads will be assessed according to inspiratory and expiratory muscle strength of each obstructive sleep apnea syndrome (OSAS) patient's.

Detailed Description

Recurrent upper airway obstruction, apnea-hypopnea events, arousals and asphyxia during sleep increase the respiratory workload in patients with OSAS. This results in chronic overload of the inspiratory muscles -especially the diaphragm- and respiratory muscle fatigue in OSAS. When the literature was checked, there was no study assessing and comparing the activities of M. genioglossus, submental muscles (upper airways dilator muscles) and diaphragm during inspiration and expiration in a workload. Differences in the activity of these muscles according to the type of respiratory maneuver will provide more appropriate respiratory muscle training in patients.

Study Timeline

• Study Start: 2019-09-16
• Study First Submitted: 2019-09-21
• Study First Submitted QC: 2019-09-23
• Study First Posted: 2019-09-25
• Primary Completion: 2021-09-14
• Study Completion: 2021-12-14
• Status Verified: 2022-01
• Last Update Submitted: 2022-01-19
• Last Update Posted: 2022-01-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• Between 35-70 years old
• Diagnosed with mild-moderate OSAS
• Clinically stabile

Exclusion Criteria

• Anatomical obstructive upper airway
• Occupations that lead to sleep deprivation or alterations in the sleep-wake cycle.
• Comorbidities such as chronic obstructive pulmonary disease, asthma, interstitial lung diseases, neuromuscular diseases and psychiatric diseases

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Respiratory muscle strength	about thirty minutes	Respiratory muscle strength will be measured with a respiratory pressure meter. Maximal inspiratory pressure and expiratory pressure were recorded.
Surface electromyographic (sEMG) measurement of submental muscles and diaphragm	about thirty minutes	Surface electromyographic (sEMG) activity of the submental muscle group (including the anterior belly of the digastric, mylohyoid, geniohyoid, and platysmas) and diaphragm will be measured during inspiratory and expiratory maneuver.
Pulmonary function test	about thirty minutes	Pulmonary function will be assessed with a portable spirometer thorough the standard procedures. Pulmonary function test results will be recorded during the inspiratory and expiratory maneuver.

Trial Locations

Locations (1)

Hacettepe University, Faculty of Pyhsical Therapy and Rehabilitation; 🇹🇷 Ankara, Turkey