Evaluation of Respiratory Muscle in Patient With Pulmonary Arterial Hypertension

Completed

• Conditions: Pulmonary Artery Hypertension
• Interventions: Diagnostic Test: patient assessment

• Registration Number: NCT05056532
• Lead Sponsor: Giresun University

Brief Summary

The aim of the study is that evaluation of basic and accessory respiratory muscles and their relationship of six minute walk test in patient with pulmonary arterial hypertension (PAH)

Detailed Description

Not available

Study Timeline

• Study Start: 2021-09-09
• Study First Submitted: 2021-09-20
• Study First Submitted QC: 2021-09-20
• Study First Posted: 2021-09-24
• Primary Completion: 2022-03-28
• Study Completion: 2022-04-18
• Status Verified: 2022-05
• Last Update Submitted: 2022-05-29
• Last Update Posted: 2022-06-01

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 52

Inclusion Criteria

• patients with diagnosis of pulmonary arterial hypertension
• patients with stabil drug therapy at least three months

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Exclusion Criteria

• patients with obstructive and/ or restrictive lung disease comorbidity
• severe orthopedic and/ or neurological comorbidity
• patients with heart failure
• patients with ischemic heart disease
• uncooperative patients

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
patients	patient assessment	Maximal mouth pressure will be evaluated for determine respiratory muscle strength, m. pectoralis, m. serratus anterior, m. sternocloideumasteoideus and quadriceps muscles strengths will be measured to evaluate accessory respiratory muscle strength, London chest activity of daily living scale will be done for assessment of dyspnea and six minute walk test will be used for determination of functionally capacity
Control group	patient assessment	Maximal mouth pressure will be evaluated for determine respiratory muscle strength, m. pectoralis, m. serratus anterior, m. sternocloideumasteoideus and quadriceps muscles strengths will be measured to evaluate accessory respiratory muscle strength, London chest activity of daily living scale will be done for assessment of dyspnea and six minute walk test will be used for determination of functionally capacity

Primary Outcome Measures

Name	Time	Method
Respiratory mouth pressure	15 minutes	Respiratory mouth pressure will be measured to determine maximally inspiratory pressure and maximally expiratory pressure according to ATS/ERS guidelines.
pectoralis muscle strength	15 minute	pectoralis muscle strength will be evaluated with hand held dynamometers according to muscle test technique
serratus anterior muscle strength	15 minutes	Serratus anterior muscle strength will be evaluated with hand held dynamometers according to muscle test technique
sternocleidomasteoideus muscle strength	15 minutes	sternocleidomasteoideus muscle strength will be evaluated with hand held dynamometers according to muscle test technique

Secondary Outcome Measures

Name	Time	Method
Six Minute Walk Test (6MWT)	30 minutes	Six minute walk test will be performed to evalute functionally exercise capacity according to ATS/ERS guidelines
Dyspnea assessment	20 minutes	London Chest Activity of Daily Living Scale will be used to sensation of dyspnea during activity of daily living.The scale consists of four domains: self-care (four items), domestic (six items), physical (two items) and leisure (three items). In total, the scale consisting of 15 items scored of 0 to 5. 0 means that "I wouldn't do anyway" and 5 means that "Someone else does it for me". Higher values indicate greater limitation due to the dyspnea

Trial Locations

Locations (1)

Istanbul university-cerrahpasa cardiology institute; 🇹🇷 Istanbul, Haseki, Turkey