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Clinical Trials/NCT03780218
NCT03780218
Completed
N/A

Evaluation of Pulmonary Function and Respiratory Muscle Strength in Patients With Burn Injury.

Hacettepe University1 site in 1 country94 target enrollmentJanuary 1, 2019
ConditionsBurns

Overview

Phase
N/A
Intervention
Not specified
Conditions
Burns
Sponsor
Hacettepe University
Enrollment
94
Locations
1
Primary Endpoint
Forced Expiratory Volume in 1 Second
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

This study evaluates the pulmonary function, respiratory muscle strength and peripheral muscle strength in patients with burn injury on the week that they will be discharge from the hospital. Healthy subjects will be evaluated for pulmonary function, respiratory muscle strength and peripheral muscle strength.

Detailed Description

Burn injures have adverse effect on the respiratory system.In addition to burn injury prolonged hospitalization may increase the ratio of respiratory complications. But, there are no information in the literature about pulmonary function, respiratory muscle strength and peripheral muscle strength in patients with burn injury. Especially, when the patients are discharged from the hospital, it is not known whether the patients are at the same level in terms of pulmonary functions respiratory muscle strength and peripheral muscle strength with healthy individuals. This study will assess pulmonary functions respiratory muscle strength and peripheral muscle strength in patients with burn injury compared to healthy subjects.

Registry
clinicaltrials.gov
Start Date
January 1, 2019
End Date
October 29, 2019
Last Updated
6 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Ozden Ozkal

Principal Investigator

Hacettepe University

Eligibility Criteria

Inclusion Criteria

  • Having a burn injury
  • Treatment by an inpatient
  • able and willing to complete the informed consent process.
  • Control group consists of healthy adults with the similar demographic characteristics as experimental group

Exclusion Criteria

  • having a pulmonary system disease
  • having a cardiac system disease
  • to do regular sports for the last three months

Outcomes

Primary Outcomes

Forced Expiratory Volume in 1 Second

Time Frame: 15 minutes

Forced Expiratory Volume in 1 Second is the volume exhaled during the first second of a forced expiratory maneuver started from the level of total lung capacity. After three trial, the best FVC value is the outcome.

Forced Vital Capacity

Time Frame: 15 minutes

is the total amount of air exhaled during the test. After three trial, the best forced vital capacity value is the outcome

Maximal Inspiratory Pressure

Time Frame: 15 minutes

is a measure of the strength of inspiratory muscles, primarily the diaphragm. It is obtained by having the patient inhale as strongly as possible against a mouthpiece. After three trial, the best value is the outcome.

Forced Expiratory Volume in 1 Second / Forced Vital Capacity

Time Frame: 15 minutes

The ratio of Forced Expiratory Volume in 1 Second / Forced Vital Capacity. This formule is calculated by measuring device. After three trial, the best value is the outcome.

Maximal Expiratory Pressure

Time Frame: 15 minutes

a measure of the strength of respiratory muscles, obtained by having the patient exhale as strongly as possible against a mouthpiece. After three trial, the best value is the outcome.

Secondary Outcomes

  • forced expiratory flow(15 minutes)
  • Functional Exercise Capacity(10 minutes)
  • Peak Expiratory Flow(15 minutes)
  • Peripheral strength(15 minutes)
  • Pain severity(15 minutes)

Study Sites (1)

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