A study to assess the thoracic epidural anaesthesia effects on pancreatic blood flow, thereby controlling disease progression in pancreatitis patients in comparison to standard care alone

Phase 3

• Conditions: Health Condition 1: K859- Acute pancreatitis, unspecified

• Registration Number: CTRI/2023/11/060287
• Lead Sponsor: Jawaharlal Institute of Postgraduate Medical Education and Research

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 19 December 2023

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

All adult patients with moderately severe acute pancreatitis admitted in JIPMER casualty within 48 hours of symptoms onset. Enrollment will be based on Modified Marshal Scoring for organ dysfunction. This score is based on

- Respiratory parameter – PaO2/FiO2

- Renal parameter – Serum creatinine

- Cardiovascular parameter- systolic BP

Each parameter will be given 0- 4 scores based on the values. A score of =2 in any one of the systems signifies organ dysfunction.

Exclusion Criteria

-Acute pancreatitis patients with coagulopathies, spine deformities, raised intracranial pressure, refractory hypotension, and skin infections at the site of injection.

-Patients with acute on chronic pancreatitis

-Pancreatitis patients with evidence of sepsis

-Patients with previous episodes of acute pancreatitis

-Patients with CKD whose GFR <30ml/min/BSA

Study & Design

• Study Type: Interventional
• Study Design: Not specified