The effect of thoracic epidural anaesthesia with general anaesthesia on mean systemic filling pressure, venous return and cardiac functio
Suspended
- Conditions
- TEAmeans systemic filling pressuresarterial- and venous resistancecardiac outputfluid loadingvasopressor
- Registration Number
- NL-OMON25658
- Lead Sponsor
- eiden University Medical Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Suspended
- Sex
- Not specified
- Target Recruitment
- 10
Inclusion Criteria
All adult patients scheduled for lung surgery under thoracic epidural and general anaesthesia
Exclusion Criteria
•Participation in a trial on investigational drugs within 3 months prior to the study
•Hemodynamic instability prior to start of measurements with the systolic blood pressure decreasing more than 30% below the pre-anaesthetic value or a mean arterial pressure (MAP) < 60 mm Hg, central venous pressure (CVP) >18 mm Hg and/ or a cardiac index < 2.0 L•min-1 or dependence on high dosages of inotropic drugs after induction of general anaesthesia and before TEA.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method -To evaluate the effects of thoracic epidural anaesthesia (TEA) under general anaesthesia on mean systemic filling pressures, arterial- and venous resistance and cardiac output
- Secondary Outcome Measures
Name Time Method -To assess the hemodynamic effects of vasopressors and fluid loading under TEA with general anaesthesia conditions<br /><br>-To assess the value of stroke volume variation and pulse pressure variation,to predict fluid loading responsiveness with TEA.<br>