TCTR20211017001尚未招募3 期
A comparative study of the effectiveness between pulse regimen methylprednisolone versus high dose dexamethasone as the initial treatment of moderate Covid-19 pneumonia: An open-label randomized controlled trial
Faculty of Medicine Ramathibodi Hospital0 个研究点目标入组 120 人开始时间: 2021年10月17日最近更新:
适应症
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 120
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 Years 至 N/A (No limit)（—）
- 性别
- All
入选标准
- •1. Age over 18 years old
- •2. Visited within 48 hours
- •3. Respiratory sample was confirmed Covid-19 by RT-PCR
- •4. Evidence of pneumonia by chest imaging
- •5. Resting oxygen saturation between 90-94%
- •6. Voluntary consent
排除标准
- •1. Recieved high flow nasal cannula, non-invasive mechanical ventilation or invasive mechanical ventilation
- •2. High risk for cortiosteroid such as current active infection or poor glycemic control
- •3. Immunocompromised host such as end stage liver disease, end stage renal disease without renal replacement therapy, HIV CD4 less than 200 or cancer with on going chemotherapy
- •4. Pregnant women
- •5. Psychiatric problems
- •6. Current use of corticosteroid (more than 20 mg of prednisolone equivalent dose and consecutively more than 14 day)
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