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The Optimal Stroke Volume Variation (SVV) for optimal fluid therapy in Major Intra-abdominal Surgeries

Not Applicable
Completed
Conditions
Not Applicable
Registration Number
KCT0001788
Lead Sponsor
Asan Medical Center
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
120
Inclusion Criteria

Stomach surgery
-Colorectal surgery (except laparoscopic surgery)
-American Society of Anesthesiologists physical status 1 or 2

Exclusion Criteria

-Laparoscopic surgery
-Arrhythmia (except sinus bradycardia and tarchycardia)
-Ischemic heart disease
-Chronic obstructive pulmonary disease
-Ascites determined by abdominal computed tomography
-Pretibial pitting edema
-Hypoalbuminemia ( <2.5 g/dL) or hypoproteinemia ( <5.5 g/dL)
-Estimated glomerular filtration rate < 60 ml/min
-Aspartate aminotransferase/Alanine aminotransferase > 100 IU/L
-Blood urea nitrogen > 30 mg/dl
-Serum creatinine > 2.0 mg/dl
-Prothrombin time > 1.5 INR
-activated partial thromboplastin time > 40 sec
-Hemoglobin < 10 g/dl
-Hematocrit < 30%
-Platelet count < 100000 per microliter
-Pacemaker inserted state
-Body weight < 40 or > 100 kg
-Systemic exposure to ICG within 24 h prior to surgery
-History of allergy to iodides

Study & Design

Study Type
Interventional Study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Time to the first passage of flatus
Secondary Outcome Measures
NameTimeMethod
Optimal stroke volume variation to minimize increase of body weight at the post-anesthesia care unit and to maintain stable hemodynamics.;Adverse events
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