A retrospective investigator-initiated study to observe the effectiveness and safety of estradiolhemihydrate tablet usage vaginally in patients with thin endometrial for endometrial preparation inFrozen Embryo Transfer (FET) cycles
Trial Snapshot
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 80
- Locations
- 1
- Primary Endpoint
- A retrospective real world observational study to observe the effectiveness and safety of estradiol
Study Overview
Brief Summary
This is a retrospective real world observational study to observe the effectiveness and safety of estradiol hemihydrate tablet usage vaginally in patients with thin endometrial for artificial endometrial preparation in Frozen Embryo Transfer (FET) cycles
Study Design
- Study Type
- Observational
Eligibility Criteria
- Ages
- 25.00 Year(s) to 42.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •Age 25 to 42 years (both inclusive) b.
- •Patients planned to undergo Frozen embryo transfer cycle where endometrial preparation will be done by hormone replacement therapy (HRT) c.
- •Normal pelvic ultrasonography.
Exclusion Criteria
- •Women who smoke b.
- •Women under 25 years or over 42 years of age c.
- •Women who had unexplained vaginal bleeding d.
- •Women who had Ashermans syndrome e.
- •Women with history of Malignancy, HIV and Tubercular endometritis g.
- •Any Contraindications for receiving estradiol h.
- •Hypersensitivity to estradiol or any of its excipients i.
Outcomes
Primary Outcomes
A retrospective real world observational study to observe the effectiveness and safety of estradiol
Time Frame: Following retrospective data will be collected in this study. | • Patients Age | • Duration and cause of Infertility | • Number of previous IVF treatment cycle | • Base line investigations | • Endometrial thickness - before starting and after administration of vaginal estradiol | hemihydrate; and on progesterone start day | • Pregnancy test - positive or negative 10 to 15 days after embryo
hemihydrate tablet usage vaginally in patients with thin endometrial for artificial endometrial
Time Frame: Following retrospective data will be collected in this study. | • Patients Age | • Duration and cause of Infertility | • Number of previous IVF treatment cycle | • Base line investigations | • Endometrial thickness - before starting and after administration of vaginal estradiol | hemihydrate; and on progesterone start day | • Pregnancy test - positive or negative 10 to 15 days after embryo
preparation in Frozen Embryo Transfer (FET) cycles
Time Frame: Following retrospective data will be collected in this study. | • Patients Age | • Duration and cause of Infertility | • Number of previous IVF treatment cycle | • Base line investigations | • Endometrial thickness - before starting and after administration of vaginal estradiol | hemihydrate; and on progesterone start day | • Pregnancy test - positive or negative 10 to 15 days after embryo
Secondary Outcomes
- NA(NA)