Dry mouth and Halitosis among Parkinson's disease patients: subjective burden versus objective measurements

• Conditions: K11.7; R19.6; G20; Disturbances of salivary secretion; Halitosis; Parkinson disease

• Registration Number: DRKS00009314
• Lead Sponsor: niklinik Köln

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2016-10-19
• Study Completion: 2017-01-01
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

PD patients: Parkinson's disease diagnosed by a neurologist, being able to self-complete the questionnaires , and provision of written informed consent

Exclusion Criteria

PD patients: evidence of a persisting or recurrent malignant disease in the head and neck region or radiation/chemotherapy in the medical history, diagnosis of diabetes, Sjögren’s syndrome or other direct medical causes of xerostomia, significant medical dental problems with pain or inflammation within the last three months, planned extensive dental treatment, deep brain stimulation, and pregnancy or planned pregnancy during the study;

Controls: disease, daily medications

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Differences between study populations in the differentiated diagnosis of the oral health situation especially with regard to dry mouth and halitosis shall be measured at one appointment with<br>1.) objective whole saliva amount measurements<br>2.) OHIPG-14 (German Version of the Oral health Impact Profile)<br>3.) Objective measurements of the Volatile Sulfur compounds for the diagnosis of halitosis with the OralChroma<br>4.) organoleptic halitosis score<br>5.) selfassessment of dry mouth and halitosis via questionnaires.