Viral Infection and Respiratory Illness Universal Study[VIRUS]: COVID-19 Registry

Completed

• Conditions: Coronavirus
• Interventions: Other: observational

• Registration Number: NCT04323787
• Lead Sponsor: Mayo Clinic

Brief Summary

Researchers are creating a real time COVID-19 registry of current ICU/hospital care patterns to allow evaluations of safety and observational effectiveness of COVID-19 practices and to determine the variations in practice across hospitals.

Detailed Description

Investigators aim is to create a real time COVID-19 registry of current ICU/hospital care patterns to allow evaluations of safety and observational effectiveness of COVID-19 practices and to determine the variations in practice across hospitals.

Such a set of standards would increase the quality of single and multi-center studies, national registries as well as aggregation syntheses such as meta-analyses. It will also be of utmost importance in tiring times of public health emergencies and will help understand practice variability and outcomes during COVID-19 pandemic.

Study Timeline

• Study First Submitted: 2020-03-24
• Study First Submitted QC: 2020-03-25
• Study First Posted: 2020-03-27
• Study Start: 2020-03-30
• Primary Completion: 2025-03-31
• Study Completion: 2025-03-31
• Status Verified: 2025-04
• Last Update Submitted: 2025-04-23
• Last Update Posted: 2025-04-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 100000

Inclusion Criteria

• COVID-19 PCR positive (within 7 days)
• COVID-19 PCR pending
• COVID-19 high clinical suspicion

Exclusion Criteria

• Patient without Prior Research Authorization (applicable to Mayo Clinic sites)
• Non COVID-19 related admissions
• Repeated Admission to ICUs/Hospital

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
COVID19 test positive/pending or high clinical suspicion	observational	COVID19 test positive/pending/high clinical suspicion- patient admitted to hospital

Primary Outcome Measures

Name	Time	Method
ICU and hospital mortality of COVID-19 patients	7 days	Primary outcome will be to measure ICU and hospital mortality up to 7 days of COVID-19 patients

Secondary Outcome Measures

Name	Time	Method
30 days mortality	30 days	Secondary outcome will be to measure 30 days mortality from Hospital discharge

Trial Locations

Locations (4)

Mayo Clinic in Arizona; 🇺🇸 Scottsdale, Arizona, United States

Mayo Clinic in Florida; 🇺🇸 Jacksonville, Florida, United States

Society of Critical Care Medicine (150+ sites); 🇺🇸 Chicago, Illinois, United States

Rahul Kashyap; 🇺🇸 Rochester, Minnesota, United States