Quality of Life Outcomes Following Minimally Invasive and Open Esophagectomy for Esophageal Cancer
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Esophageal Cancer
- Sponsor
- Memorial Sloan Kettering Cancer Center
- Enrollment
- 257
- Locations
- 1
- Primary Endpoint
- short-term pain
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
The goal of this study is to evaluate how surgery for esophageal cancer affects the patient's quality of life over time. The investigators hope this study will provide important information that can be used to improve the quality of life of patients with esophageal cancer. This study will also look at how standard tests and information collected from the patients difficulty swallowing can predict the extent of their esophageal cancer before surgery.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Age 18 or older
- •Diagnosis of esophageal cancer, stages I-IIIC, with no prior esophageal resection. Neoadjuvant therapy given prior to presentation at MSKCC will be accepted.
- •Anticipated to undergo surgical resection (Ivor Lewis, Trans Hiatal, thoracoabdominal, or McKeown procedure) of esophageal cancer either by open or minimally invasive methods
- •Chest and abdomen CT scan
- •Ability to speak read and write English.
Exclusion Criteria
- •Inability to give informed consent
- •Patients requiring a laryngectomy or colon interposition as part of their surgical resection.
- •Patients with scleroderma.
Outcomes
Primary Outcomes
short-term pain
Time Frame: 4 months
Pain intensity (average of the four pain severity items) measured by BPI at Post-op Days 1 and 3, after epidural removal, at first post-operative clinic visit, at 4 months
short -term quality of life (QOL)
Time Frame: 4 months
FACT-E score at the post-op visit and at the 4 months
Secondary Outcomes
- Complications(90 days)
- long time quality of life (QOL)(2 years)
- long-term pain(2 years)
- differences in surgical outcomes(90 days)