Detection of dysplastic and neoplastic lesions in patients with Barrett’s esophagus through exhaled breath using an electronic nose device (eNose)
- Conditions
- Barrett's esophagus, dysplasia, esophageal adenocarcinoma
- Registration Number
- NL-OMON24189
- Lead Sponsor
- Radboud university medical center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Other
- Sex
- Not specified
- Target Recruitment
- 75
Inclusion Criteria
Subjects, who are/have:
- Aged 18 years or older.
Exclusion Criteria
- Patients with a history of any type of malignancy except for esophageal adenocarcinoma and non-melanoma skin cancer.
- Patients with prior history of ablation (photodynamic therapy, radiofrequency ablation, cryotherapy, argon plasma coagulation) or endoscopic mucosal resection.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The ability to differentiate between BE patients with dysplastic or neoplastic lesions and patients with NDBE by eNose in terms of sensitivity, specificity and accuracy.
- Secondary Outcome Measures
Name Time Method - Cross-validated accuracy with which the eNose can distinguish between BE patients with dysplastic or neoplastic lesions and patients with NDBE, defined as the percentage of correctly classified patients using the leave-some out method.<br>-Acceptance rate of using the eNose