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Endocytoscopic identification of dysplasia in the Barrett’s esophagus using artificial intelligence as a second assessor: a prospective assessment of the interaction between gastroenterologists and a convolutional neural network

Completed
Conditions
Barrett's esophagus, (low/high grade) dysplasia, esophageal adenocarcinoma
Registration Number
NL-OMON27377
Lead Sponsor
niversity Medical Center Groningen (UMCG)
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
52
Inclusion Criteria

oPatients with established BE scheduled for gastroscopy due to surveillance examination;
oPatients with established BE and a malignant visible lesion scheduled for gastroscopy due to endoscopic mucosal resection (EMR) or Endoscopic Submucosal Dissection (ESD).
oAge = 18 years;
oWritten informed consent.

Exclusion Criteria

oAge younger than 18 years
oInability to give written informed consent for the study

Study & Design

Study Type
Observational non invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Diagnostic accuracy is defined as sensitivity, specificity, predictive value and likelihood ratio’s. Measures: true positives, true negatives, false positives and false negatives of endocytoscopy procedure. Gold standard for comparison is the histopathological result of biopsy which will be extracted from reports of patients’ digital medical chart for which they will have to provide consent.
Secondary Outcome Measures
NameTimeMethod
<br>Kappa values for inter-observer agreement. <br>Procedural qualities will consist of the rating of image quality and additional procedural time for making endocytoscopic images. <br>Basic demographic data: gender, year of birth.
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