Quantifying Electropathology in Adult Patients with Congenital Interatrial Communications an endocardial mapping study

• Conditions: congenital heart defect; Congenital heart disease; 10007521; 10007510; 10007593

• Registration Number: NL-OMON51978
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 30

Inclusion Criteria

>=18 years;
Scheduled for elective endovascular closure of atrial septal defect or patent
foramen ovale

Exclusion Criteria

Paced atrial rhythms
Pacemaker/ internal cardiac defibrillator (ICD)
Hemodynamic instability
Presence of assist devices
Use of inotropic agents
Emergency endovascular cardiac procedures
Left ventricle ejection fraction < 30%
Severe kidney or liver failure
Receiving local anaesthesia

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Quantification of electrophysiological parameters obtained from endocardial<br /><br>mapping that determine the degree of electropathology: conduction block,<br /><br>conduction delay, conduction velocity, signal morphology (voltage,<br /><br>fractionation). These parameters will be correlated with electropathology,<br /><br>atrial ectopy, atrial volume, clinical characteristics and features of pre- and<br /><br>post-procedural atrial fibrillation.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>N.a.</p><br>