The ARCHER Study - understanding how puberty hormone change affects health, wellbeing and behaviour in Australian adolescents living in regional New South Wales
Not Applicable
Active, not recruiting
- Conditions
- Puberty hormonesMetabolic and Endocrine - Normal metabolism and endocrine development and function
- Registration Number
- ACTRN12617000964314
- Lead Sponsor
- Kate Steinbeck
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Active, not recruiting
- Sex
- All
- Target Recruitment
- 400
Inclusion Criteria
Healthy, normally developing adolescents living in the study recruitment catchment areas around Orange and Dubbo in regional NSW
Exclusion Criteria
1. Adolescent intellectual disability
2. Lack of English competency in the adolescent
3. Lack of English competency in the parent/guardian
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change in first-morning urinary testosterone analysed via liquid chromatography mass spectrometry[Years 1 to 3: every three months<br>Years 4 to 6: every six months<br><br>N.B. Urine collection is stepped down to six-monthly collection after the third year of follow-up (the majority of participants will have gone through puberty by then), in order to reduce participant burden.<br><br>The primary outcome is the pattern of change in this hormone, thus there is no primary end point per se.];Change in first-morning urinary oestradiol analysed via liquid chromatography mass spectrometry[Years 1 to 3: every three months<br>Years 4 to 6: every six months<br><br>N.B. Urine collection is stepped down to six-monthly collection after the third year of follow-up (the majority of participants will have gone through puberty by then), in order to reduce participant burden.<br><br>The primary outcome is the pattern of change in this hormone, thus there is no primary end point per se.]
- Secondary Outcome Measures
Name Time Method