Dopamine modulation of oxytocin prosocial effects
- Conditions
- HEALTHY VOLUNTEERS. FOR PATIENTS WITH AUTISM OR SCHIZOPHRENIATherapeutic area: Psychiatry and Psychology [F] - Behaviours [F01]
- Registration Number
- EUCTR2011-006302-28-IT
- Lead Sponsor
- IVERSITA' DEGLI STUDI DI PARMA
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Authorised-recruitment may be ongoing or finished
- Sex
- Male
- Target Recruitment
- 50
Inclusion Criteria
Male Caucasian, healthy subjects (age: 18-44 years) with negative history of neurological, medical and psychiatric diseases.
Are the trial subjects under 18? no
Number of subjects for this age range: 0
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 50
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range
Exclusion Criteria
-negative history of neurological, medical and psychiatric diseases
-< 18 years
-> 55 years
- women
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Main Objective: Characterize dopaminergic D2 system modulation on prosocial responses to oxytocin;Secondary Objective: Multimodal identification of cerebral responses associated with oxytocin;Primary end point(s): Cerebral and social behavior responses to intranasal oxytocin administration in genetic variants of D2 system;Timepoint(s) of evaluation of this end point: 3 years
- Secondary Outcome Measures
Name Time Method Secondary end point(s): Cerebral and social behavior responses to intranasal oxytocin administration in genetic variants of D2 system;Timepoint(s) of evaluation of this end point: 3 years