Effects of Oxytocin on Socio-Cognitive Processes: New Insights from Spatio-Temporal EEG Analyses
Not Applicable
- Conditions
- Healthy subjects.
- Registration Number
- DRKS00017150
- Lead Sponsor
- niversitätsklinikum Freiburg, vertreten durch Prof. Dr. Frederik Wenz
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 169
Inclusion Criteria
Caucasian
- Single
- interested in the opposite sex
- no mental or physical illness
Exclusion Criteria
- consumption of drugs as well as heavy alcohol drinkers and smokers
- body mass index >=30
- left handed people
- psychology and economics students and graduates
- not being fluent in German
- nasal spray allergies
for women:
- pregnancy
- hormone contraceptives
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Behavior:<br>Trusting decisions, modulated by the within-subjects factors threat (high vs. low) and attractiveness (high vs. low) and the between-subjects factor gender. Trust is quantified by the number of decisions in which points were transferred to the interaction partner in the trust game (dichotomous decision: keep points vs. transfer points). There are 84 decisions, 21 in each condition (e.g. high threat, high attractiveness). <br><br>Brain: Using electroencephalography to determine<br>ERPs (e.g., P100, LPP) during trusting decisions modulated by the factors threat, attractiveness, and gender. ERPs are quantified by amplitude values (uV) at specific time points.
- Secondary Outcome Measures
Name Time Method We will collect self-report measures on dispositional social reward sensitivity (Social Reward Questionnaire), social anxiety (Liebowitz Social Anxiety Scale), interpersonal trust (Interpersonal Trust Scale) socio-communicative skills (Autism-spectrum quotient), and pre- and post-experimental mood ratings (Positive and Negative Affect Schedule). We will check whether values in the self-report scale moderate oxytocin effects.