The Effect of Oxytocin on Cognitive Rigidity and Social Anxiety in Eating Disorders
Phase 1
Completed
- Conditions
- Anorexia NervosaMental Health - Eating disorders
- Registration Number
- ACTRN12611000671965
- Lead Sponsor
- The Centre for Eating and Dieting Disorders (CEDD)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Female
- Target Recruitment
- 80
Inclusion Criteria
Participants who meet DSM-IV diagnostic criteria for Anorexia Nervosa will be included in the study. Participants suffering from common comorbidities of depression and anxiety and Axis II disorders will be included in the study.
Exclusion Criteria
Participants will be exluded from the trial if they are suffering from any other major conditions, apart from those related to anorexia nervosa (i.e. common comorbidities of depression, anxiety and Axis II disorders)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method evel of social anxiety measured by The Liebowitz Social Anxiety Scale (LSAS; Liebowitz, 1987)[Measured pre treatment (Week 0) and post treatment (week 6)];Level of cognitive rigidity measured by the Brixton Task (Burgess and Shallice, 1997)[Measured pre treatment (Week 0) and post treatment (week 6)]
- Secondary Outcome Measures
Name Time Method Changes in cognitive functioning assessed using a range of measures including: 1. The Eye-Gaze Task (Guastella, Mitchell, & Dadds, 2008) 2. Reading the Mind in the Eyes Test (RMET, Baron-Cohen et al 2001) 3. Wisconsin Card Sorting Test (Heaton et al, 1993) 4. The Pictorial/Emotional Stroop task (Ashwin et al. 2006; Williams et al. 1996) 5. The Working Alliance Inventory-Short Form (Therapist and Participant versions) (Hatcher & Gillaspy, 2006) 6. The Obsessive-Compulsive Inventory-Revised (OCI-R; Foa et al., 2002)[Measured at four time points - pre-treatment (week 0), week 3, post treatment (week 6) and three week follow up at week 9.]