Does oxytocin influence consciousness and suggestibility?

Phase 1

• Conditions: There are no medical conditions or diseases under investigation; MedDRA version: 19.1Level: PTClassification code 10033334Term: Oxytocin normalSystem Organ Class: 10022891 - Investigations; Therapeutic area: Not possible to specify

• Registration Number: EUCTR2016-004826-40-SE
• Lead Sponsor: Department of Psychology, Stockholm University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-12-21
• Last Update Posted: 2 June 2020

Recruitment & Eligibility

• Status: ot Recruiting
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

- Healthy women and men 18-30 years old
- Fluent SWedish
- Right-handed
- Live in the Stockholm area
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 120
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

- Pregnacy
- Breastfeeding
- Nasal allergies
- Sesame or nuts allergy
- Any known neurological, visual, and auditory impairment
- Use of medication (except oral contraceptives)
- Drug or alcohol abuse
- Psychiatric disorder
- Nasal disease or obstruction
- Smoking
- Claustrophobia (fear to close rooms/spaces
- Fear to dark rooms/spaces

Study & Design

• Study Type: Interventional clinical trial of medicinal product
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Main Objective: Examine whether OXT facilitates the occurrence and affects the quality of spiritual experiences and the sensed presence of a sentient being.;Secondary Objective: - Determine whether oxytocin receptor polymorphism contributes to spiritual experience and the sensed presence of a sentient being, either in itself or in combination with exteroceptive oxytocin administration. <br>- Study whether individual differences in personality dispositions (attachment, propensities for ”absorption”, philosophy of life) further contribute to the outcomes.;Primary end point(s): Descriptions of sensory experiences during deprivation (dark room,no noise). The descriptions will be written by the participants themselves.;Timepoint(s) of evaluation of this end point: 45 minutes after administration of oxytocin or placebo

Secondary Outcome Measures

Name	Time	Method
Secondary end point(s): Self-reported inventories that focus on personality, affiliation, philosophical and spiritual experiences;Timepoint(s) of evaluation of this end point: After the description of sensory deprivation