Behavioral effects and neural correlates of oxytocin on social attention [Verhaltenseffekte und neuronales Korrelat von Oxytocin im Kontext sozialer Aufmerksamkeit]

Phase 1

• Conditions: subjects with autism spectrum disorder and neurotypical controls; MedDRA version: 12.1Level: LLTClassification code 10063844Term: Autism spectrum disorder

• Registration Number: EUCTR2010-022511-18-DE
• Lead Sponsor: Albert-Ludwig University Freiburg, Laboratory for Biological and Personality Psychology

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2010-12-06
• Last Update Posted: 2 June 2020

Recruitment & Eligibility

• Status: ot Recruiting
• Sex: Male
• Target Recruitment: 100

Inclusion Criteria

- age: 18 - 50 years
- ASD-group only: diagnosed autism spectrum disorder (DSM-IV: 299.00, 299.80)
- male
- right-handed
- non-smoker
- German native-speaker
- normal or corrected-to-normal vision
- written informed-consent

Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

- somatic illness
- endocrinological or psychoactive medication
- controls only: current or past diagnosis of neurological or psychiatric disorder
- ASD-group only: dominant psychiatric comorbidity (DSM-IV axis I / II)
- on the day of behavioral testing: caffeinated beverages and alcohol; drinking or eating anything except water for two hours before testing
- hypersensitivity towards the active substance or other ingredients (e.g. preservatives like parabens)
- fMRI-group only: non-MRI-compatible conditions (e.g. metal in body)
- mental retardation (IQ < 70)
- speech development disorder

Study & Design

• Study Type: Interventional clinical trial of medicinal product
• Study Design: Not specified