This study is to find out which antibiotic injection is better for treating infection of the abdominal fluid in patients with liver disease.
Not Applicable
Completed
- Conditions
- Health Condition 1: K652- Spontaneous bacterial peritonitis
- Registration Number
- CTRI/2022/11/047518
- Lead Sponsor
- JIPMER
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 68
Inclusion Criteria
Cirrhosis patients, in whom there is a clinical suspicion of SBP or ascitic fluid has more than 250 polymorphonuclear cells on microscopy will be included in this study.
Exclusion Criteria
Following patients will be excluded
Secondary bacterial peritonitis
Peritonial tuberculosis
Patient with hepto cellular carcinoma
Previous cultures positive for resistant bacteria to third generation cephalosporins
Allergy to third generation cephalosporin
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.To compare early resolution rates of SBP after 48 hours of antibiotic administration between the two groups <br/ ><br>2. To compare the resolution rates of SBP after 7 days of antibiotic administration between the two groupsTimepoint: 48 hours and 7 days
- Secondary Outcome Measures
Name Time Method 1. To compare the proportion of patients who develop new organ failure at 48 hours in the two groups using SOFA Score <br/ ><br>2. To compare the mortality rates between the two groups at 30 and 90 days <br/ ><br>3. To compare the length of hospital stay between the two groupsTimepoint: 48 hours, 30 days, 90 days