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Zinc Sulfate add-on therapy compared to risperidone alone in schizophrenia: a double-blind, randomized, placebo-controlled clinical trial

Phase 2
Conditions
Schizophrenia.
Schizophrenia, unspecified
Registration Number
IRCT138801241457N3
Lead Sponsor
Mazandaran University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
30
Inclusion Criteria

DSM-IV-TR criteria for schizophrenia, PANSS score more than 80, no anti psychotic consumption or seven half-life, the drug was wash out
Exclusion criteria: other psychiatric disorders such as substance dependence and physical illnesses, such as liver and renal failure, cardiovascular diseases, allergic and immune system disorders etc.

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Severity of symptoms. Timepoint: Baseline and 2nd, 4th, and 6th week. Method of measurement: Positive and Negative Syndrome Scale (PANSS).
Secondary Outcome Measures
NameTimeMethod
The speed of risperidone antipsychotic effect. Timepoint: Baseline and 2nd, 4th, and 6th week. Method of measurement: Positive and Negative Syndrome Scale (PANSS).
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